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Rap1GAP Polyclonal Antibody, 50ul Reservoirs Overexpression of this gene has

SKU: 33373908171

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Rap1GAP Polyclonal Antibody, 50ul Reservoirs Overexpression of this gene hasRAP1GAP encodes a type of GTPase activating protein (GAP) that down regulates the activity of the ras related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP bound form and an active GTP bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating

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Description

Overexpression of this gene has been observed in some cancer cells

which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily

In this form| it circulates in the plasma| prolonging the half-life of IGFs and altering their interaction with cell surface receptors

The protein encoded by this gene belongs to the G-protein coupled receptor 1 family

CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis

Rap1GAP Polyclonal Antibody, 50ul Reservoirs Overexpression of this gene hasRAP1GAP encodes a type of GTPase activating protein (GAP) that down regulates the activity of the ras related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP bound form and an active GTP bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating

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