Dvl-2 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation chromosomal aberrations involving this gene

chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors

This gene encodes a member of the G-protein-coupled receptor 1 family

The LRP2 protein is critical for the reuptake of numerous ligands

is a dimer composed of disulfide-linked heavy and light chains

Belongs to the cation channel sperm-associated family

Dvl-2 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation chromosomal aberrations involving this geneDVL2 encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. DVL2 encodes a 90 kD protein that undergoes posttranslational phosphorylation to form a 95 kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved