PAK gamma(Phospho Ser20) Polyclonal Antibody, 100ul Cell Screening and Imaging Charcot-Marie-Tooth disease type 4E (CMT4E)

Charcot-Marie-Tooth disease type 4E (CMT4E)

Higher levels of expression of RPL31 in familial adenomatous polyps compared to matched normal tissues have been observed

Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis

Three distinct forms

encodes a diadenosine 5'

PAK gamma(Phospho Ser20) Polyclonal Antibody, 100ul Cell Screening and Imaging Charcot-Marie-Tooth disease type 4E (CMT4E)The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, and may play a role