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ZO-2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases This gene encodes a member

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ZO-2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases This gene encodes a memberTJP2 (tight junction protein 2) encodes a zonula occluden that is a member of the membrane associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in TJP2 have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal

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Description

This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation

A highly-similar gene encoding a related protein is also found on chromosome 1

MET encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET

The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene

Prostaglandin reductase 1 specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4

ZO-2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases This gene encodes a memberTJP2 (tight junction protein 2) encodes a zonula occluden that is a member of the membrane associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in TJP2 have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal

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