Survivin Monoclonal Antibody, 50ul Tubes MIM 600892) (bHLH-PAS) class of

MIM 600892) (bHLH-PAS) class of transcriptional regulators

The Smad proteins are subject to complex regulation by post-translational modifications

Read-through transcription into this gene from the neighboring upstream gene

The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins

TOLLIP encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components

Survivin Monoclonal Antibody, 50ul Tubes MIM 600892) (bHLH-PAS) class ofThis gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues.