p70 S6 Kinase alpha Polyclonal Antibody, 20ul[BT-AP12704] Human Genome Knockout Libraries E3 ubiquitin ligases accept ubiquitin

E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates

This kinase can be activated by phospholipids and by limited proteolysis

This protein contains 6 WD repeats and is highly expressed in the heart

a multisystem developmental disorder

Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons

p70 S6 Kinase alpha Polyclonal Antibody, 20ul[BT-AP12704] Human Genome Knockout Libraries E3 ubiquitin ligases accept ubiquitinThis gene encodes a member of the ribosomal S6 kinase family of serine threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N