Artn Polyclonal Antibody, 20ul Virus Packaging Mutations in NOTCH4 may be

Mutations in NOTCH4 may be associated with schizophrenia

An important paralog of this gene is ZNF169

A pseudogene of this gene is found on chromosome 16

transferring glycosyl groups and N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity

Several alternatively spliced transcript variants encoding different isoforms have been described for MED23

Artn Polyclonal Antibody, 20ul Virus Packaging Mutations in NOTCH4 may beThis gene encodes a secreted ligand of the glial cell line derived neurotrophic factor (GDNF) subfamily and TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer.