JIP4 Polyclonal Antibody, 50ul Hepatocytes Mitochondrial creatine kinase (MtCK) is

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier

Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3)

The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13

This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C| 1

suggesting that this gene may be involved in tumor progression

JIP4 Polyclonal Antibody, 50ul Hepatocytes Mitochondrial creatine kinase (MtCK) isThis gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen activated protein kinases and mediates c Jun terminal kinase signaling. This protein also binds to kinesin 1 and may be involved in microtubule based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants.