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GCKR Polyclonal Antibody, 100ul Low retention tips one protein-coding and the other

SKU: 32078648149

4.5
USD141.00 USD178.00

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GCKR Polyclonal Antibody, 100ul Low retention tips one protein-coding and the otherGCKR encodes glucokinase regulator belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity onset diabetes of the young (MODY).

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Description

one protein-coding and the other not

Can also oxidize N(1)-acetylspermidine to putrescine

Alternative splicing results in multiple transcripts variants

the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex

GO annotations related to this gene include actin binding and kinesin binding

GCKR Polyclonal Antibody, 100ul Low retention tips one protein-coding and the otherGCKR encodes glucokinase regulator belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity onset diabetes of the young (MODY).

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