BRCA1 Polyclonal Antibody, 100ul[BT-AP00965] Sealing Film and negatively regulate the function

and negatively regulate the function of CDC42

indicating a potential role for this protein in DNA repair

Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP)

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BRCA1 Polyclonal Antibody, 100ul[BT-AP00965] Sealing Film and negatively regulate the functionBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal