PTEN Monoclonal Antibody, 50ul Site-directed Mutagenesis and expression of this gene

and expression of this gene may be altered in tumors

REG4 (Regenerating Family Member 4) is a Protein Coding gene

The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells

This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination

Together with metastasis-associated protein-2

PTEN Monoclonal Antibody, 50ul Site-directed Mutagenesis and expression of this geneThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide