ATR Polyclonal Antibody, 50ul Centrifuges CDC25B (cell division cycle 25B)

CDC25B (cell division cycle 25B) is a member of the CDC25 family of phosphatases

The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein

Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins

Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes

It is located in the membranes of outgrowing axons and has been shown to be important for axonal outgrowth during development and regenerative sprouting

ATR Polyclonal Antibody, 50ul Centrifuges CDC25B (cell division cycle 25B)The protein encoded by ATR (ATR serine threonine kinase) belongs the PI3 PI4 kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1,