PKD1 Polyclonal Antibody, 100ul[BT-AP13117] Lysosome Mutations in this gene are

Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2

It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells

the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase

Interacts with the PDZ domain of SHANK1

resulting in downregulation of their active form

PKD1 Polyclonal Antibody, 100ul[BT-AP13117] Lysosome Mutations in this gene arePRKD1 is a serine threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009