CK8 Monoclonal Antibody(8G8), 20ul Cellular Function Assays Mutations in this gene are

Mutations in this gene are associated with several congenital defects

Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region

Multiple alternatively spliced transcript variants of CDC25C have been described

A chromosomal aberration involving PRDM3 is found in a form of acute myeloid leukemia

Store it at 2-8℃ for optimal results

CK8 Monoclonal Antibody(8G8), 20ul Cellular Function Assays Mutations in this gene areThis gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal