EphB1/2/3 Polyclonal Antibody, 50ul Metabolic enzymes GRK5 encodes a member of

GRK5 encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family

This encoded protein binds p120 (RasGAP) from CML cells

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It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein

Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity

EphB1/2/3 Polyclonal Antibody, 50ul Metabolic enzymes GRK5 encodes a member ofEphrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity