MKK7(Phospho-Ser271/Thr275) Rabbit Polyclonal Antibody, 20ul Cellular Cultivation & Health Management Defects in this gene are

Defects in this gene are the cause of glycogen storage disease II| also known as Pompe's disease| which is an autosomal recessive disorder with a broad clinical spectrum

or RHO proteins

Several transcript variants encoding different isoforms have been described for this gene

and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration

Made from GPPS material

MKK7(Phospho-Ser271/Thr275) Rabbit Polyclonal Antibody, 20ul Cellular Cultivation & Health Management Defects in this gene areThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8 JNK1 and MAPK9 JNK2 and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1 MEKK1 MAP3K2 MEKK2 MAP3K3 MEKK5 and MAP4K2 GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines and environmental