OTUB2 Polyclonal Antibody, 100ul Recombinant Protein Expression The enzyme may play a

The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin

CCKAR (cholecystokinin A receptor) encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones

subcellular location:Present in the major dense line of CNS myelin

Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2)

Mutations in this gene are associated with slow-channel congenital myasthenic syndrome

OTUB2 Polyclonal Antibody, 100ul Recombinant Protein Expression The enzyme may play aOTUB2 encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. OTU deubiquitinase, ubiquitin aldehyde binding 2 contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain.