Rat Aquaporin 2, AQP-2 ELISA Kit, 96T Virus Packaging A microdeletion in the region

A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib

and induction of long-term depression at parallel fiber-Purkinje cell synapses (PubMed: 16234806)

disease:Defects in MT-ATP6 are a cause of infantile bilateral striatal necrosis

resulting in phase resetting of the cerebral cortex clock (By similarity)

providing the precursor for eicosanoid biosynthesis via the cyclooxygenase pathway

Rat Aquaporin 2, AQP-2 ELISA Kit, 96T Virus Packaging A microdeletion in the regionForms a water specific Channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient (PubMed: 8429910, PubMed: 7508187). Plays an essential role in renal water homeostasis (By similarity).