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Ets-1(Phospho Ser251) Polyclonal Antibody, 50ul High Speed Micro-Centrifuges Allelic variations in this gene

SKU: 30208282786

4.1
USD162.00 USD197.00

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Ets-1(Phospho Ser251) Polyclonal Antibody, 50ul High Speed Micro-Centrifuges Allelic variations in this geneThis gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA binding domain that recognizes the core consensus DNA sequence GGAA T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding

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Description

Allelic variations in this gene have been associated| but not causally linked| with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS)

With this kit

which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762)

An important paralog of this gene is AKT1

This gene functionally complements Chinese hamster irs1SF

Ets-1(Phospho Ser251) Polyclonal Antibody, 50ul High Speed Micro-Centrifuges Allelic variations in this geneThis gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA binding domain that recognizes the core consensus DNA sequence GGAA T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding

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