Histone H2B (Tri Methyl Lys5) Polyclonal Antibody, 50ul miRNA / siRNA Synthesis Mutations in this gene have

Mutations in this gene have been associated with Johanson-Blizzard syndrome

and age-related macular degeneration type 3 (ARMD3)

induction:Up-regulated in T-cells following TCR engagement

Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported

CDC25A is required for progression from G1 to the S phase of the cell cycle

Histone H2B (Tri Methyl Lys5) Polyclonal Antibody, 50ul miRNA / siRNA Synthesis Mutations in this gene haveHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.