BGH3 Polyclonal Antibody, 100ul Recombinant Ab Production Aberrant expression of this gene

Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types

It plays an important role in neuronal development and function

endonuclease FEN1 cleavage activity on substrates with double| nick| or gap flaps of distinct sequences and lengths

An important paralog of this gene is TAAR9

The encoded protein was originally identified as an important component of glomerular podocytes

BGH3 Polyclonal Antibody, 100ul Recombinant Ab Production Aberrant expression of this geneThis gene encodes an RGD containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor beta and acts to inhibit cell adhesion.