p53(Phospho Thr18) Polyclonal Antibody, 100ul Cell Function Analysis This gene was identified by

This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease

both protein coding and non-protein coding

Mutations in this gene are associated with forebrain defects

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RIN1 is localized primarily to the plasma membrane

p53(Phospho Thr18) Polyclonal Antibody, 100ul Cell Function Analysis This gene was identified byThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.