SPTC2 Rabbit Polyclonal Antibody, 100ul Lysosome DUSP14 contains the consensus DUSP

DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al

PGC (progastricsin) encodes an aspartic proteinase that belongs to the peptidase family A1

An important paralog of this gene is GPR21

The encoded protein is a zinc-dependent metallopeptidase that catalyzes the removal of an amino acid from the amino terminus of a protein or peptide

The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor| known as somatoliberin| which acts to stimulate growth hormone release from the pituitary gland

SPTC2 Rabbit Polyclonal Antibody, 100ul Lysosome DUSP14 contains the consensus DUSPThis gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase which consists of two different subunits is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal 5 prime phosphate dependent condensation of L serine and palmitoyl CoA to 3 oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.