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APC Polyclonal Antibody, 100ul[BT-AP00506] Lysosome and cyclin-dependent kinase inhibitor 1B

SKU: 29056002193

4.8
USD123.75 USD169.75

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APC Polyclonal Antibody, 100ul[BT-AP00506] Lysosome and cyclin-dependent kinase inhibitor 1BAPC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre malignant disease that usually progresses to malignancy. Disease associated mutations tend to be clustered in a small region designated the

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Description

and cyclin-dependent kinase inhibitor 1B

Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor

catalyzes the formation of phosphoenolpyruvate from oxaloacetate

then this is known to affect dendritic spine morphology and formation---this is thought to occur through the Rac1/PAK1/LIMK/CFL1 pathway

the first step in the synthesis of GDP-fucose from GDP-mannose

APC Polyclonal Antibody, 100ul[BT-AP00506] Lysosome and cyclin-dependent kinase inhibitor 1BAPC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre malignant disease that usually progresses to malignancy. Disease associated mutations tend to be clustered in a small region designated the

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