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ER Alpha Monoclonal Antibody, 100ul[BT-MCA0514] Nucleic Acid Isolation & Purification APBA3 is a candidate gene

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ER Alpha Monoclonal Antibody, 100ul[BT-MCA0514] Nucleic Acid Isolation & Purification APBA3 is a candidate geneThis gene encodes an estrogen receptor, a ligand activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen

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Description

APBA3 is a candidate gene for Alzheimer's disease

The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule

This protein (apoptotic peptidase activating factor 1) contains several copies of the WD-40 domain

The encoded protein is found in a centrosomal complex with FEZ1

Alternatively spliced transcript variants encoding different isoforms have been identified for HOXC6

ER Alpha Monoclonal Antibody, 100ul[BT-MCA0514] Nucleic Acid Isolation & Purification APBA3 is a candidate geneThis gene encodes an estrogen receptor, a ligand activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen

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