MKP-2 Polyclonal Antibody, 100ul Mammalian Expression The product of this gene

The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes

The protein encoded by this gene contains a caspase recruitment domain (CARD)

which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762)

may interact with and regulate effector molecules (Gilman

which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis

MKP-2 Polyclonal Antibody, 100ul Mammalian Expression The product of this geneThe dual specificity phosphatase 4 encoded by DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine threonine and phosphotyrosine residues. They negatively regulate members of the mitogen activated protein (MAP) kinase superfamily (MAPK ERK, SAPK JNK, p38), which are associated with cellular proliferation and differentiation. Different