CD45 Monoclonal Antibody, 50ul Lysosome Alternative splicing is the basis

Alternative splicing is the basis for the structural and functional diversity of this protein

the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway

Additional variants have been described

Apoptosis antagonizing transcription factor encoded by AATF was identified on the basis of its interaction with MAP3K12/DLK

KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM)

CD45 Monoclonal Antibody, 50ul Lysosome Alternative splicing is the basisThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been