IGF-IR Polyclonal Antibody, 50ul[BT-AP04399] Cell Culture Flasks Studies in mice suggest that

Studies in mice suggest that this gene functions in wound healing and abdominal wall development

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guinea pig

Contains 11 LRR (leucine-rich) repeats

The protein encoded by this gene belongs to the GHMP (galacto-

IGF-IR Polyclonal Antibody, 50ul[BT-AP04399] Cell Culture Flasks Studies in mice suggest thatIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms