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HXD11 Polyclonal Antibody, 20ul Cryopreservation LFA-1 plays a central role

SKU: 27540440540

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PLN111.00 PLN160.00

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HXD11 Polyclonal Antibody, 20ul Cryopreservation LFA-1 plays a central roleThis gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2.

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Description

LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands

Several transcripts encoding different isoforms have been found for this gene

Binding of its ligand| hepatocyte growth factor| induces dimerization and activation of the receptor| which plays a role in cellular survival| embryogenesis| and cellular migration and invasion

It is similar to a rat protein which is a specific partner for the tail domain of myosin V

Directly mediates protection against viral and bacterial genital infections (By similarity)

HXD11 Polyclonal Antibody, 20ul Cryopreservation LFA-1 plays a central roleThis gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2.

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