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QPCT Rabbit Polyclonal Antibody, 20ul Immunoassays APM2 gene is exclusively expressed

SKU: 27066846119

4.2
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QPCT Rabbit Polyclonal Antibody, 20ul Immunoassays APM2 gene is exclusively expressedThis gene encodes human pituitary glutaminyl cyclase which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase.

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Description

APM2 gene is exclusively expressed in adipose tissue

catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate

are found in a cluster on chromosome 1

The chromosomal rearrangements are the most common genetic alterations in this gene| which result in creation of multiple fusion genes in tumourigenesis| including ALK (chromosome 2)/EML4 (chromosome 2)| ALK/RANBP2 (chromosome 2)| ALK/ATIC (chromosome 2)| ALK/TFG (chromosome 3)| ALK/NPM1 (chromosome 5)| ALK/SQSTM1 (chromosome

This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1

QPCT Rabbit Polyclonal Antibody, 20ul Immunoassays APM2 gene is exclusively expressedThis gene encodes human pituitary glutaminyl cyclase which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase.

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