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GRP3 Polyclonal Antibody, 100ul Deep Well Plates Component of the NF-kappa-B p52-c-Rel

SKU: 26867311880

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SEK123.75 SEK149.75

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GRP3 Polyclonal Antibody, 100ul Deep Well Plates Component of the NF-kappa-B p52-c-RelMembers of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP GDP regulated switches that cycle between inactive GDP and active GTP bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000

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Description

Component of the NF-kappa-B p52-c-Rel complex

Mutations in this gene or its regulatory region cause hypobetalipoproteinemia| normotriglyceridemic hypobetalipoproteinemia| and hypercholesterolemia due to ligand-defective apoB| diseases affecting plasma cholesterol and apoB levels

Two pseudogenes have been identified on chromosome 15

XRCC5 functionally complements Chinese hamster xrs-6

Alternatively spliced transcript variants encoding different isoforms have been noted for ITGA7

GRP3 Polyclonal Antibody, 100ul Deep Well Plates Component of the NF-kappa-B p52-c-RelMembers of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP GDP regulated switches that cycle between inactive GDP and active GTP bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000

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