GABP- Alpha Monoclonal Antibody, 50ul Peptide Synthesis BCL2 binding component 3 cooperates

BCL2 binding component 3 cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis

This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers

GO annotations related to this gene include transcription factor activity

Related pseudogenes have been identified on chromosomes 7 and 14

Periphilin 1 encoded by PPHLN1 is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis

GABP- Alpha Monoclonal Antibody, 50ul Peptide Synthesis BCL2 binding component 3 cooperatesThis gene encodes one of three GA binding protein transcription factor subunits which functions as a DNA binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for