AS160(Phospho-Ser318) Rabbit Polyclonal Antibody, 20ul Virus Packaging Defects in this gene are

Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2)

NR1I3 (nuclear receptor subfamily 1 group I member 3) encodes a member of the nuclear receptor superfamily

and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy

The protein encoded by this gene is a class I PI3K found primarily in leukocytes

which is a huntingtin binding protein that may function in vesicle trafficking

AS160(Phospho-Ser318) Rabbit Polyclonal Antibody, 20ul Virus Packaging Defects in this gene areThis gene is a member of the Tre 2 BUB2 CDC16 domain family. The protein encoded by this gene is a Rab GTPase activating protein and contains two phopshotyrosine binding domains (PTB1 and PTB2) a calmodulin binding domain (CBD) a Rab GTPase domain and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin dependent trafficking of the glucose transporter 4 (GLUT4) important for