Ku-70 (Acetyl Lys331) Polyclonal Antibody, 100ul Centrifugal Filter Alternative splice variants that encode

Alternative splice variants that encode different protein isoforms have been described

100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31

X-linked disorder occurring at a frequency of about 1 in 3

Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor

these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2

Ku-70 (Acetyl Lys331) Polyclonal Antibody, 100ul Centrifugal Filter Alternative splice variants that encodeThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with