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Axl Polyclonal Antibody, 50ul[BT-AP00783] Peptide Synthesis The protein encoded by LEPR

SKU: 26220798164

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Axl Polyclonal Antibody, 50ul[BT-AP00783] Peptide Synthesis The protein encoded by LEPRThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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Description

The protein encoded by LEPR belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins

including lung

MALT1 and this protein are thought to synergize in the activation of NF-kappaB

Polymorphisms in this protein appear to be tissue specific and influence protease targeting

with a strong preference for the latter

Axl Polyclonal Antibody, 50ul[BT-AP00783] Peptide Synthesis The protein encoded by LEPRThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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