c-Src(Phospho Tyr419) Polyclonal Antibody, 100ul[BT-AP06923] Bio-Reaction Tube This locus encodes a member

This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins

The protein is primarily expressed in brain

IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al

The encoded protein can multimerize and may function as an ion channel

EPH and EPH-related receptors have been implicated in mediating developmental events| particularly in the nervous system

c-Src(Phospho Tyr419) Polyclonal Antibody, 100ul[BT-AP06923] Bio-Reaction Tube This locus encodes a memberThis gene is highly similar to the v src gene of Rous sarcoma virus. This proto oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine protein kinase whose activity can be inhibited by phosphorylation by c SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for