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Ku-70 Polyclonal Antibody, 50ul[BT-AP04896] Aspirating Pipets interacts with major histocompatibility complex

SKU: 24707410769

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Ku-70 Polyclonal Antibody, 50ul[BT-AP04896] Aspirating Pipets interacts with major histocompatibility complexThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

interacts with major histocompatibility complex class I ligands

It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination

is released from HMWK

a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes

Two transcript variants encoding the same protein have been found for KRT18

Ku-70 Polyclonal Antibody, 50ul[BT-AP04896] Aspirating Pipets interacts with major histocompatibility complexThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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