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NFATc2IP Polyclonal Antibody, 100ul Peptide Library There are multiple isoforms of

SKU: 24646323917

4.4
SEK123.75 SEK157.75

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NFATc2IP Polyclonal Antibody, 100ul Peptide Library There are multiple isoforms ofNFATC2IP, also named as NIP45, is a 419 amino acid protein, which contains one ubiquitin like domain. TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. NFATC2IP In T helper 2 (Th2) cells, regulates the magnitude of NFAT driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2.

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Description

There are multiple isoforms of each of the proteins in the complex

Interacts with RNF43

This gene encodes a member of the syntaxin superfamily

thus is thought to be a candidate tumor suppressor gene

The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA)

NFATc2IP Polyclonal Antibody, 100ul Peptide Library There are multiple isoforms ofNFATC2IP, also named as NIP45, is a 419 amino acid protein, which contains one ubiquitin like domain. TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. NFATC2IP In T helper 2 (Th2) cells, regulates the magnitude of NFAT driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2.

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