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Rb Polyclonal Antibody, 100ul[BT-AP07686] Vessels Studies of the rat counterpart

SKU: 24381194506

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Rb Polyclonal Antibody, 100ul[BT-AP07686] Vessels Studies of the rat counterpartThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

Studies of the rat counterpart suggest that the encoded protein may function as a receptor for adrenomedullin

Serum level of this protein

Cyclin F encoded by CCNF belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified

The protein (BCL2 like 11) encoded by BCL2L11 belongs to the BCL-2 protein family

and large extracellular loops containing multiple N-glycosylation sites

Rb Polyclonal Antibody, 100ul[BT-AP07686] Vessels Studies of the rat counterpartThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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