c-Rel(Phospho Ser503) Polyclonal Antibody, 50ul Buffers & Solutions Complex I is localized to

Complex I is localized to the inner mitochondrial membrane and functions to dehydrogenate nicotinamide adenine dinucleotide and to shuttle electrons to coenzyme Q

This protein may regulate neuronal proliferation and has been implicated in the progression of glioblastoma through its ability to dephosphorylate the p53 tumor suppressor

cofactor:Binds 2 zinc ions per subunit

but no functional distinctions have been identified among the four variants

Associates with the clathrin-associated adapter protein complex 2 (AP-2)

c-Rel(Phospho Ser503) Polyclonal Antibody, 50ul Buffers & Solutions Complex I is localized toThis gene encodes a protein that belongs to the Rel homology domain immunoglobulin like fold, plexin, transcription factor (RHD IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B cell lymphomas, including Hodgkin's lymphoma.