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Pepsin C Polyclonal Antibody, 50ul CellSafe™ Transcript variants encoding different isoforms

SKU: 24134573979

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Pepsin C Polyclonal Antibody, 50ul CellSafe™ Transcript variants encoding different isoformsPGC (progastricsin) encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the

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Description

Transcript variants encoding different isoforms have been noted for CYP11B1

which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation

leaving a small fragment termed CLIP (class-II-associated invariant chain peptide)

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK)

Humans have multiple pseudogenes of this gene

Pepsin C Polyclonal Antibody, 50ul CellSafe™ Transcript variants encoding different isoformsPGC (progastricsin) encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the

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