GASP-1 Polyclonal Antibody, 50ul High Speed Micro-Centrifuges This cytokine is a ligand

This cytokine is a ligand for receptor TNFRSF18/AITR/GITR

Three members of this gene family have been studied in detail and are estimated to generate over 3000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member

The upstream stimulatory factor 2 can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs and is involved in regulating multiple cellular processes

When translation ends upstream from the last exon-exon junction| this triggers NMD to degrade mRNAs containing premature stop codons

The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP

GASP-1 Polyclonal Antibody, 50ul High Speed Micro-Centrifuges This cytokine is a ligandGPRASP1 (G protein coupled receptor associated sorting protein 1) encodes a member of the GPRASP (G protein coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down regulation of a variety of G protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta