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p53 Rabbit Polyclonal Antibody, 100ul[BT-AP11724] Pipette Controller Alternative splicing results in multiple

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p53 Rabbit Polyclonal Antibody, 100ul[BT-AP11724] Pipette Controller Alternative splicing results in multipleThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

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Description

Alternative splicing results in multiple transcript variants encoding different protein isoforms

The DNA repair protein complementing XP-A cells is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens

They may participate in fatty acyl and cholesterol ester metabolism| and may play a role in the blood-brain barrier system

Mutations in TPH1 have been associated with an elevated risk for a variety of diseases and disorders

The tenascins have anti-adhesive effects

p53 Rabbit Polyclonal Antibody, 100ul[BT-AP11724] Pipette Controller Alternative splicing results in multipleThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

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