RFX5 Rabbit Polyclonal Antibody, 100ul Funnels Type I and II receptors

Type I and II receptors form a stable complex after ligand binding

The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration

This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family

Defects in this gene can result in three different disorders

and two most abundant spliced variants encode the somatic form and the testicular form

RFX5 Rabbit Polyclonal Antibody, 100ul Funnels Type I and II receptorsA lack of MHC II expression results in a severe immunodeficiency syndrome called MHC II deficiency or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B cell lines established from patients with BLS. The molecular defects in complementation groups B C and D all lead to a deficiency in RFX a nuclear protein complex that binds to the X box of MHC II promoters. The lack of RFX binding activity in