DSC3 Polyclonal Antibody, 100ul Plasmid Preparation Patients with mutations in this

Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain

It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3

and may also have a role in controlling cell growth and/or differentiation

An important paralog of this gene is JMJD7-PLA2G4B

This gene encodes a member of the GIT protein family| which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity

DSC3 Polyclonal Antibody, 100ul Plasmid Preparation Patients with mutations in thisThe protein encoded by this gene is a calcium dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on