I23O1 Polyclonal Antibody, 100ul Antibodies The RING finger and B-box

The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions

The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1

Cytokines are small proteins that have an essential role in the immune and inflammatory responses

Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity

ssential component of the eNoSC (energy-dependent nucleolar silencing) complex

I23O1 Polyclonal Antibody, 100ul Antibodies The RING finger and B-boxThis gene encodes indoleamine 2,3 dioxygenase (IDO) a heme enzyme that catalyzes the first and rate limiting step in tryptophan catabolism to N formyl kynurenine. This enzyme acts on multiple tryptophan substrates including D tryptophan, L tryptophan, 5 hydroxy tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology,