ERAP1 Polyclonal Antibody, 20ul sgRNA Library Construction RBR E3 ubiquitin protein ligase

RBR E3 ubiquitin protein ligase contains two RING-finger motifs and an in between RING fingers motif

Alternatively spliced transcript variants have been found for BLNK

It acts as a homodimer in striated muscle as well as in other tissues

Cytochrome P450 family 21 subfamily A member 2 localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position

The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase

ERAP1 Polyclonal Antibody, 20ul sgRNA Library Construction RBR E3 ubiquitin protein ligaseEndoplasmic reticulum aminopeptidase 1 encoded by ERAP1 is an aminopeptidase involved in trimming HLA class I binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for ERAP1.