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Nanog Monoclonal Antibody, 100ul Recombinant Protein Expression Increased expression of this gene

SKU: 22666713888

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Nanog Monoclonal Antibody, 100ul Recombinant Protein Expression Increased expression of this geneThe protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation, renewal, and pluripotency. The encoded protein can block ES cell differentiation and can also autorepress its own expression in differentiating cells. Two transcript variants encoding different isoforms have been found for this gene.

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Description

Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling

Has a function in binding of osteoblasts via the alpha(V)beta(3)-integrin

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases

This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains

as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele

Nanog Monoclonal Antibody, 100ul Recombinant Protein Expression Increased expression of this geneThe protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation, renewal, and pluripotency. The encoded protein can block ES cell differentiation and can also autorepress its own expression in differentiating cells. Two transcript variants encoding different isoforms have been found for this gene.

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