CIC Polyclonal Antibody, 50ul Electrophoresis & Labeling Contains 1 PUA domain

Contains 1 PUA domain

Mutations in this gene are associated with gastrointestinal stromal tumors| mast cell disease| acute myelogenous lukemia| and piebaldism

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta

Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading

including EPO

CIC Polyclonal Antibody, 50ul Electrophoresis & Labeling Contains 1 PUA domainThe protein encoded by this gene is an ortholog of the Drosophila melanogaster capicua gene, and is a member of the high mobility group (HMG) box superfamily of transcriptional repressors. This protein contains a conserved HMG domain that is involved in DNA binding and nuclear localization, and a conserved C terminus. Studies suggest that the N terminal region of this protein interacts with Atxn1 (GeneID: 6310), to form a transcription repressor