HACE1 Polyclonal Antibody, 50ul Site-directed Mutagenesis Could have a dual role

Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping

and epidermal growth factor receptor/protein kinase B signaling during tumor pathogenesis

Stickler syndrome type I

This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities

the intact fusion protein can be specifically eluted from the resin by the addition of excess free maltose

HACE1 Polyclonal Antibody, 50ul Site-directed Mutagenesis Could have a dual roleThis gene encodes a HECT domain and ankyrin repeat containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor.